James Cook Week 13 Preview vs. the 49ers

James Cook has a decent matchup when his Buffalo Bills play the San Francisco 49ers in Week 13 (Sunday, 8:20 PM ET). The 49ers have allowed 110.8 rushing yards per game, 11th in the NFL.

On 137 carries this year, Cook has rushed for a team-best 596 yards (59.6 ypg). He has scored 10 TDs on the ground. Cook has also made his mark as a pass-catcher, grabbing 25 balls for 182 yards (18.2 ypg) and one touchdown.

Watch this game on Fubo (Regional restrictions may apply).

Cook vs. the 49ers

• Cook vs the 49ers (since 2021): No games
• The 49ers have let one opposing rusher to pile up 100 or more yards in a game during the 2024 season.
• San Francisco has allowed 12 opposing rushers to record one or more TDs on the groun against them this year.
• Three opposing rushers have scored two or more TDs on the ground against the 49ers this season.
• The 110.8 rushing yards per game allowed by the 49ers defense makes them the NFL's 11th-ranked run defense.
• Opponents of the 49ers have scored 16 touchdowns on the ground (1.5 per game). The 49ers' defense is 29th in the NFL in that category.

Catch every NFL touchdown with NFL RedZone on Fubo.

Cook Rushing Insights

• So far this season, Cook has hit the over five times on his rushing yards prop bet (in 10 opportunities).
• The Bills pass on 52.7% of their plays and run on 47.3%. They are fourth in NFL action in points scored.
• He has handled 44.6% of his team's 307 rushing attempts this season (137).
• Cook has a rushing touchdown in seven games this season, including multiple rushing TDs three times.
• He has 30.6% of his team's 36 offensive touchdowns this season (11).
• He has 31 red zone carries for 43.1% of the team share (his team runs on 62.1% of its plays in the red zone).

Get in the game and sign up for FanDuel Fantasy today. Use our link to start playing daily fantasy.

Cook's Recent Performance